nucleus
| GENENAME | LOCUSLINK | FOLD CHANGE | LOCUSLINK CLASSIFICATIONS |
|---|---|---|---|
| activity-dependent neuroprotective protein | 11538 | 2.53189 | DNA binding; neuropeptide hormone activity; neuropeptide signaling pathway; nucleus; regulation of transcription, DNA-dependent; transcription factor activity |
| amyloid beta (A4) precursor-like protein 2 | 11804 | 1.43603 | DNA binding; endopeptidase inhibitor activity; extracellular space; integral to membrane; nucleus; serine-type endopeptidase inhibitor activity |
| aryl hydrocarbon receptor nuclear translocator | 11863 | 2.77673 | DNA binding; cytoplasm; nucleus; protein binding; receptor activity; regulation of transcription; regulation of transcription, DNA-dependent; response to toxin; signal transducer activity; signal transduction; transcription factor activity; transcription factor complex; transcriptional activator activity |
| activating transcription factor 1 | 11908 | 1.68331 | DNA binding; cysteine protease inhibitor activity; nucleus; protein binding; regulation of transcription, DNA-dependent; transcription factor activity; transcription factor complex |
| heterogeneous nuclear ribonucleoprotein D | 11991 | 1.59678 | DNA binding; RNA binding; chromosome, telomeric region; nucleic acid binding; nucleus; regulation of transcription, DNA-dependent; ribonucleoprotein complex; telomerase-dependent telomere maintenance |
| Bcl2-associated athanogene 1 | 12017 | 1.49433 | apoptosis; chaperone activity; cytosol; neuron differentiation; nucleus; protein binding; regulation of apoptosis |
| BarH-like homeobox 1 | 12022 | 4.5894 | DNA binding; nucleus; regulation of transcription, DNA-dependent; transcription factor activity; transcription factor complex |
| budding uninhibited by benzimidazoles 3 homolog (S. cerevisiae) | 12237 | 1.62671 | nucleus |
| cyclin A2 | 12428 | 2.28072 | cell cycle; cyclin-dependent protein kinase regulator activity; cytokinesis; mitosis; nucleus; regulation of cell cycle |
| cyclin B2 | 12442 | 3.53872 | cell cycle; cyclin-dependent protein kinase regulator activity; cytokinesis; mitosis; nucleus; regulation of cell cycle |
| cyclin-dependent kinase 2 | 12566 | 2.26267 | ATP binding; cell cycle; cyclin-dependent protein kinase activity; cyclin-dependent protein kinase holoenzyme complex; cytokinesis; kinase activity; mitosis; nucleus; protein amino acid phosphorylation; protein binding; protein kinase activity; protein serine/threonine kinase activity; transcription factor complex; transferase activity |
| centromere autoantigen A | 12615 | 1.81624 | DNA binding; chromosome; chromosome organization and biogenesis (sensu Eukarya); chromosome, pericentric region; nucleosome; nucleosome assembly; nucleus |
| cofilin 2, muscle | 12632 | 1.7167 | actin binding; cytoskeleton; intracellular; nucleus |
| cAMP responsive element binding protein-like 1 | 12915 | 3.14182 | DNA binding; endoplasmic reticulum; integral to membrane; nucleus; regulation of transcription, DNA-dependent; response to unfolded protein |
| Fas death domain-associated protein | 13163 | 3.47068 | PML body; nucleus; protein binding; transcriptional repressor activity |
| D site albumin promoter binding protein | 13170 | 5.67315 | DNA binding; circadian rhythm; nucleus; regulation of transcription, DNA-dependent; rhythmic behavior |
| distal-less homeobox 2 | 13392 | 1.7825 | DNA binding; cell differentiation; development; nucleus; regulation of transcription, DNA-dependent; transcription factor activity; transcription factor complex |
| dentatorubral pallidoluysian atrophy | 13498 | 1.64992 | cytoplasm; nucleus; toxin metabolism; toxin receptor binding |
| ets variant gene 6 (TEL oncogene) | 14011 | 3.69839 | DNA binding; cell differentiation; cell growth and/or maintenance; intracellular; nucleus; protein binding; regulation of cell cycle; regulation of transcription, DNA-dependent; transcription factor activity |
| Ewing sarcoma homolog | 14030 | 1.7204 | DNA binding; RNA binding; calmodulin binding; nucleic acid binding; nucleus; regulation of transcription, DNA-dependent |
| forkhead box M1 | 14235 | 1.58943 | DNA binding; nucleus; regulation of transcription, DNA-dependent; transcription factor activity; transcription factor complex |
| fragile X mental retardation syndrome 1 homolog | 14265 | 2.0639 | RNA binding; central nervous system development; nucleic acid binding; nucleus |
| amino-terminal enhancer of split | 14797 | 1.29986 | negative regulation of transcription; nucleus; protein binding; regulation of growth; skeletal development; transcription corepressor activity |
| goosecoid | 14836 | 1.66594 | DNA binding; development; nucleus; regulation of transcription, DNA-dependent; transcription factor activity |
| glutathione S-transferase, theta 1 | 14871 | 2.75857 | glutathione metabolism; glutathione transferase activity; nucleus; transferase activity |
| homeodomain interacting protein kinase 2 | 15258 | 1.80352 | ATP binding; PML body; cytoplasm; kinase activity; negative regulation of transcription from Pol II promoter; nucleus; protein amino acid phosphorylation; protein kinase activity; protein serine/threonine kinase activity; transcription corepressor activity; transferase activity |
| high mobility group nucleosomal binding domain 2 | 15331 | 2.09436 | DNA binding; DNA packaging; chromatin; nucleus |
| nuclear receptor subfamily 4, group A, member 1 | 15370 | 3.45432 | DNA binding; inhibition of caspase activation; ligand-dependent nuclear receptor activity; nucleus; receptor activity; regulation of transcription, DNA-dependent; steroid hormone receptor activity; transcription factor activity |
| heterogeneous nuclear ribonucleoprotein A/B | 15384 | 1.56487 | DNA binding; RNA binding; RNA processing; nucleic acid binding; nucleus; regulation of transcription, DNA-dependent; ribonucleoprotein complex; viral nucleocapsid |
| inner centromere protein | 16319 | 1.44862 | cell cycle; chromosome, pericentric region; cytokinesis; mitosis; nucleus |
| Jun proto-oncogene related gene d1 | 16478 | 2.60892 | DNA binding; cell growth and/or maintenance; intracellular; nucleus; regulation of cell cycle; regulation of transcription, DNA-dependent; transcription factor activity |
| Kruppel-like factor 3 (basic) | 16599 | 2.24876 | DNA binding; nucleus; regulation of transcription, DNA-dependent |
| LIM domain only 4 | 16911 | 2.67317 | protein binding; transcription factor binding; transcription factor complex; transcription from Pol II promoter |
| mago-nashi homolog, proliferation-associated (Drosophila) | 17149 | 1.84365 | female gamete generation; nucleus; sex determination |
| minichromosome maintenance deficient 5, cell division cycle 46 (S. cerevisiae) | 17218 | 1.327 | ATP binding; DNA binding; DNA replication; DNA replication initiation; DNA-dependent ATPase activity; nucleus; regulation of transcription, DNA-dependent |
| myocyte enhancer factor 2A | 17258 | 5.40759 | DNA binding; nucleus; regulation of transcription, DNA-dependent; transcription factor activity |
| midline 1 | 17318 | 2.2221 | intracellular; nucleus; regulation of transcription, DNA-dependent; zinc ion binding |
| Msx-interacting-zinc finger | 17344 | 1.48948 | DNA binding; RNA polymerase II transcription factor activity; nucleus; transcription, DNA-dependent |
| myeloid ecotropic viral integration site-related gene 1 | 17536 | 3.10515 | DNA binding; eye morphogenesis; nucleus; regulation of transcription, DNA-dependent; transcription factor activity |
| Max interacting protein 1 | 17859 | 3.72034 | DNA binding; nucleus; protein binding; regulation of transcription, DNA-dependent |
| nuclear receptor coactivator 3 | 17979 | 2.18478 | nucleus; regulation of transcription, DNA-dependent; signal transducer activity; signal transduction; transferase activity |
| nuclear factor I/C | 18029 | 1.51328 | DNA binding; DNA replication; intracellular; nucleus; odontogenesis (sensu Vertebrata); regulation of transcription, DNA-dependent; transcription factor activity |
| nuclear factor I/X | 18032 | 3.71001 | DNA binding; DNA replication; intracellular; nucleus; regulation of transcription, DNA-dependent; transcription factor activity |
| nuclear respiratory factor 1 | 18181 | 1.7387 | DNA binding; carbohydrate metabolism; mitochondrion organization and biogenesis; nucleus; regulation of transcription, DNA-dependent; transcription factor activity; transcription factor complex |
| N-terminal Asn amidase | 18203 | 1.60155 | adult locomotory behavior; cytoplasm; hydrolase activity; memory; nucleus; protein N-terminal asparagine amidohydrolase activity |
| 8-oxoguanine DNA-glycosylase 1 | 18294 | 3.58126 | DNA N-glycosylase activity; DNA binding; DNA repair; base-excision repair; carbohydrate metabolism; catalytic activity; endonuclease activity; hydrolase activity; hydrolase activity, acting on glycosyl bonds; lyase activity; mitochondrion; nuclease activity; nucleus; oxidized base lesion DNA N-glycosylase activity; purine-specific oxidized base lesion DNA N-glycosylase activity |
| pre B-cell leukemia transcription factor 3 | 18516 | 2.80889 | DNA binding; anterior compartment specification; nucleus; posterior compartment specification; regulation of transcription, DNA-dependent; transcription factor activity; transcription factor complex |
| period homolog 3 (Drosophila) | 18628 | 2.23063 | circadian rhythm; nucleus; regulation of transcription, DNA-dependent; rhythmic behavior; signal transducer activity; signal transduction |
| protein kinase, cAMP dependent, catalytic, alpha | 18747 | 1.8799 | ATP binding; cAMP-dependent protein kinase activity; cytoplasm; mesoderm formation; nucleus; protein amino acid phosphorylation; protein kinase activity; protein serine/threonine kinase activity; protein-tyrosine kinase activity; transferase activity |
| polymerase (DNA directed), alpha 2 | 18969 | 1.71072 | DNA replication; nucleus |
| polymerase (DNA directed), delta 2, regulatory subunit | 18972 | 2.1568 | DNA replication; DNA-directed DNA polymerase activity; nucleus; transferase activity |
| polymerase (DNA directed), epsilon 2 (p59 subunit) | 18974 | 1.59047 | DNA binding; DNA replication; DNA-directed DNA polymerase activity; nucleus; transferase activity |
| CCR4-NOT transcription complex, subunit 7 | 18983 | 2.45237 | CCR4-NOT complex; nucleus; positive regulation of transcription from Pol II promoter; protein binding; regulation of transcription, DNA-dependent; transcriptional activator activity |
| peroxisome proliferator activated receptor gamma | 19016 | 3.91878 | DNA binding; adipocyte differentiation; cytosol; inflammatory response; ligand-dependent nuclear receptor activity; nucleus; receptor activity; regulation of transcription, DNA-dependent; steroid hormone receptor activity; transcription factor activity |
| protein kinase, AMP-activated, gamma 1 non-catalytic subunit | 19082 | 1.19904 | SNF1A/AMP-activated protein kinase activity; fatty acid biosynthesis; kinase activity; nucleus; response to stress |
| retinoic acid receptor, gamma | 19411 | 1.64145 | DNA binding; ligand-dependent nuclear receptor activity; nucleus; receptor activity; regulation of transcription, DNA-dependent; retinoic acid receptor activity; steroid hormone receptor activity; transcription; transcription factor activity |
| retinoblastoma-like 1 (p107) | 19650 | 1.79321 | cell cycle; negative regulation of cell cycle; nucleus; protein binding; regulation of transcription, DNA-dependent; transcription factor complex |
| RNA binding motif protein, X chromosome | 19655 | 1.98812 | RNA binding; nucleic acid binding; nucleus; ribonucleoprotein complex; viral nucleocapsid |
| v-rel reticuloendotheliosis viral oncogene homolog A (avian) | 19697 | 1.63241 | DNA binding; cell growth and/or maintenance; cytoplasm; defense response; nucleus; organogenesis; positive regulation of interleukin-12 biosynthesis; positive regulation of transcription, DNA-dependent; protein binding; regulation of cell cycle; regulation of transcription, DNA-dependent; transcription factor activity; transcriptional activator activity |
| D4, zinc and double PHD fingers family 2 | 19708 | 1.48267 | DNA binding; apoptosis; nucleus; regulation of transcription, DNA-dependent |
| ring finger protein 1 | 19763 | 1.8625 | chromatin modification; nuclear body; nucleus; protein binding; regulation of transcription, DNA-dependent; transcriptional repressor activity; zinc ion binding |
| splicing factor 3a, subunit 2 | 20222 | 1.6352 | RNA binding; mRNA processing; nuclear mRNA splicing, via spliceosome; nucleic acid binding; nucleus; pre-mRNA splicing factor activity; spliceosome complex |
| sine oculis-related homeobox 2 homolog (Drosophila) | 20472 | 1.4255 | DNA binding; development; nucleus; regulation of transcription, DNA-dependent; transcription factor activity; transcription factor complex |
| nuclear receptor co-repressor 2 | 20602 | 1.78452 | DNA binding; nucleus; receptor activity; regulation of transcription, DNA-dependent |
| stromal antigen 1 | 20842 | 1.76618 | cell cycle; chromosome segregation; mitosis; nucleus |
| basic helix-loop-helix domain containing, class B2 | 20893 | 1.70733 | DNA binding; negative regulation of transcription, DNA-dependent; nucleus; protein binding; regulation of transcription, DNA-dependent; transcriptional repressor activity |
| suppressor of variegation 3-9 homolog 1 (Drosophila) | 20937 | 1.82373 | DNA packaging; chromatin; chromatin assembly/disassembly; chromatin binding; chromatin modification; methyltransferase activity; nuclear heterochromatin; nucleus; protein methyltransferase activity; transferase activity |
| TATA box binding protein | 21374 | 2.01117 | DNA binding; RNA polymerase I transcription factor complex; RNA polymerase II transcription factor activity; nucleus; protein binding; regulation of transcription, DNA-dependent; transcription; transcription factor TFIID complex; transcription factor activity; transcription factor complex; transcription initiation from Pol II promoter |
| transcription factor EB | 21425 | 1.82398 | DNA binding; nucleus; regulation of transcription, DNA-dependent; transcription factor activity; transcription factor complex |
| upstream binding transcription factor, RNA polymerase I | 21429 | 1.7925 | DNA binding; nucleolus; nucleus; protein binding; regulation of transcription, DNA-dependent; transcription factor activity; transcription factor complex |
| thymine DNA glycosylase | 21665 | 1.93159 | DNA repair; carbohydrate metabolism; hydrolase activity; hydrolase activity, acting on glycosyl bonds; nucleus; protein targeting |
| thyrotroph embryonic factor | 21685 | 2.10475 | double-stranded DNA binding; nucleus; positive regulation of transcription from Pol II promoter; protein binding; transcriptional activator activity |
| transforming growth factor beta 1 induced transcript 4 | 21807 | 2.34809 | nucleus; regulation of transcription, DNA-dependent; transcription factor activity |
| thyroid hormone receptor alpha | 21833 | 3.34439 | cartilage condensation; cell growth and/or maintenance; nucleus; organogenesis; ossification; physiological process; receptor activity; regulation of cell cycle; regulation of heart rate; regulation of transcription, DNA-dependent; thyroid hormone receptor activity; transcription factor activity |
| TGFB inducible early growth response 1 | 21847 | 1.96799 | DNA binding; nucleus; regulation of transcription, DNA-dependent |
| transformation related protein 53 | 22059 | 1.52863 | DNA binding; DNA damage response, signal transduction by p53 class mediator; apoptosis; cytoplasm; cytosol; negative regulation of cell cycle; nucleus; protein binding; protein-nucleus import, translocation; regulation of cell proliferation; regulation of transcription, DNA-dependent; transcription; transcription factor activity |
| twist gene homolog 1 (Drosophila) | 22160 | 1.91125 | DNA binding; cell differentiation; development; limb morphogenesis; neurulation; nucleus; regulation of transcription, DNA-dependent |
| ubiquitously transcribed tetratricopeptide repeat gene, Y chromosome | 22290 | 2.53162 | membrane; nucleus; receptor activity; transport; transporter activity |
| vitamin D receptor | 22337 | 1.76451 | DNA binding; calcium ion homeostasis; calcium ion transport; development; intestinal absorption; ligand-dependent nuclear receptor activity; nucleus; organogenesis; receptor activity; regulation of transcription, DNA-dependent; skeletal development; steroid hormone receptor activity; transcription; transcription factor activity |
| zinc finger protein 162 | 22668 | 1.75027 | RNA binding; mRNA processing; nuclear mRNA splicing, via spliceosome; nucleic acid binding; nucleus; regulation of transcription, DNA-dependent; spliceosome complex |
| zinc finger protein 97 | 22759 | 2.37681 | DNA binding; nucleic acid binding; nucleus |
| zinc finger protein, multitype 2 | 22762 | 2.28297 | cytoplasm; negative regulation of transcription from Pol II promoter; nucleic acid binding; nucleus; transcription corepressor activity |
| zinc finger homeobox 1b | 24136 | 3.43035 | DNA binding; neural crest cell migration; nucleus; regulation of transcription, DNA-dependent; transcription factor activity |
| heat shock transcription factor 4 | 26386 | 2.67805 | DNA binding; heat shock protein activity; nucleus; regulation of transcription, DNA-dependent; transcription factor activity |
| mitogen activated protein kinase 3 | 26417 | 1.36076 | ATP binding; MAP kinase activity; cell cycle; cytoplasm; kinase activity; nucleus; organogenesis; phosphorylation; phosphotyrosine binding; protein amino acid phosphorylation; protein binding; protein kinase activity; protein serine/threonine kinase activity; protein-tyrosine kinase activity; signal transduction; transferase activity |
| G protein-coupled receptor kinase-interactor 2 | 26431 | 1.80547 | DNA binding; GTPase activator activity; kinase activity; nucleus; protein binding; receptor activity |
| nucleosome assembly protein 1-like 1 | 53605 | 1.51213 | DNA binding; nucleosome assembly; nucleus |
| small nuclear ribonucleoprotein polypeptide A | 53607 | 1.52373 | RNA binding; nucleic acid binding; nucleus; ribonucleoprotein complex; spliceosome complex |
| HLA-B-associated transcript 1A | 53817 | 2.21707 | ATP binding; ATP-dependent RNA helicase activity; ATP-dependent helicase activity; ATPase activity; RNA binding; helicase activity; hydrolase activity; nucleic acid binding; nucleus |
| RING1 and YY1 binding protein | 56353 | 2.08641 | negative regulation of transcription from Pol II promoter; nucleoplasm; nucleus; protein binding; transcription corepressor activity |
| A kinase (PRKA) anchor protein 8 | 56399 | 2.73109 | DNA binding; kinase activity; nucleus |
| origin recognition complex, subunit 6-like (S. cerevisiae) | 56452 | 2.54755 | DNA binding; DNA replication; nucleus |
| ribosomal protein S6 kinase, polypeptide 4 | 56613 | 1.74279 | ATP binding; catalytic activity; nucleus; protein amino acid phosphorylation; protein kinase activity; protein serine/threonine kinase activity; protein-tyrosine kinase activity; transferase activity |
| ring finger protein 14 | 56736 | 1.9344 | ligase activity; nucleus; regulation of transcription, DNA-dependent |
| REC8-like 1 (yeast) | 56739 | 1.73159 | meiosis; nucleus; protein binding; synaptonemal complex |
| ubiquitin specific protease 49 | 56771 | 1.75577 | biological_process unknown; cellular_component unknown; molecular_function unknown; nucleus; regulation of transcription, DNA-dependent |
| RIKEN cDNA E130014G12 gene | 56805 | 3.4174 | nucleus; protein binding; transcription |