protein binding
| GENENAME | LOCUSLINK | FOLD CHANGE | LOCUSLINK CLASSIFICATIONS |
|---|---|---|---|
| adducin 1 (alpha) | 11518 | 1.53772 | calmodulin binding; cytoskeleton; membrane; structural molecule activity |
| aryl-hydrocarbon receptor-interacting protein | 11632 | 1.65183 | protein folding; transcription cofactor activity; xenobiotic metabolism |
| aryl hydrocarbon receptor nuclear translocator | 11863 | 2.77673 | DNA binding; cytoplasm; nucleus; protein binding; receptor activity; regulation of transcription; regulation of transcription, DNA-dependent; response to toxin; signal transducer activity; signal transduction; transcription factor activity; transcription factor complex; transcriptional activator activity |
| activating transcription factor 1 | 11908 | 1.68331 | DNA binding; cysteine protease inhibitor activity; nucleus; protein binding; regulation of transcription, DNA-dependent; transcription factor activity; transcription factor complex |
| Bcl2-associated athanogene 1 | 12017 | 1.49433 | apoptosis; chaperone activity; cytosol; neuron differentiation; nucleus; protein binding; regulation of apoptosis |
| bone morphogenetic protein 4 | 12159 | 2.32949 | BMP signaling pathway; cell fate commitment; cytokine activity; extracellular space; growth; growth factor activity; heart development; mesoderm cell fate determination; metanephros development; protein binding; skeletal development; ureteric bud development |
| calmodulin 2 | 12314 | 1.97335 | G-protein coupled receptor protein signaling pathway; calcium ion binding; cell cycle; cytoplasm; plasma membrane; protein binding |
| CD9 antigen | 12527 | 3.1168 | integral to membrane; plasma membrane; protein binding |
| cyclin-dependent kinase 2 | 12566 | 2.26267 | ATP binding; cell cycle; cyclin-dependent protein kinase activity; cyclin-dependent protein kinase holoenzyme complex; cytokinesis; kinase activity; mitosis; nucleus; protein amino acid phosphorylation; protein binding; protein kinase activity; protein serine/threonine kinase activity; transcription factor complex; transferase activity |
| cofilin 2, muscle | 12632 | 1.7167 | actin binding; cytoskeleton; intracellular; nucleus |
| Fas death domain-associated protein | 13163 | 3.47068 | PML body; nucleus; protein binding; transcriptional repressor activity |
| discs, large homolog 1 (Drosophila) | 13383 | 1.9973 | basolateral plasma membrane; protein binding |
| eukaryotic translation initiation factor 4E binding protein 2 | 13688 | 2.32937 | cAMP-mediated signaling; cellular_component unknown; insulin receptor signaling pathway; protein binding; regulation of protein biosynthesis; regulation of translation; regulation of translational initiation |
| ets variant gene 6 (TEL oncogene) | 14011 | 3.69839 | DNA binding; cell differentiation; cell growth and/or maintenance; intracellular; nucleus; protein binding; regulation of cell cycle; regulation of transcription, DNA-dependent; transcription factor activity |
| Ewing sarcoma homolog | 14030 | 1.7204 | DNA binding; RNA binding; calmodulin binding; nucleic acid binding; nucleus; regulation of transcription, DNA-dependent |
| fibroblast growth factor 2 | 14173 | 1.90451 | angiogenesis; cell proliferation; extracellular space; fibroblast growth factor receptor binding; glial cell differentiation; growth factor activity; heparin binding; positive regulation of cell differentiation; protein binding; regulation of cell cycle; regulation of retinal programmed cell death; signal transduction |
| c-fos induced growth factor | 14205 | 2.28257 | angiogenesis; cell growth and/or maintenance; cell proliferation; extracellular; growth factor activity; membrane; protein binding; regulation of cell cycle; vascular endothelial growth factor receptor binding |
| growth factor receptor bound protein 10 | 14783 | 1.97947 | SH3/SH2 adaptor protein activity; cytosol; insulin-like growth factor receptor signaling pathway; intracellular signaling cascade; neuropeptide signaling pathway; protein binding; receptor activity; signal transduction |
| amino-terminal enhancer of split | 14797 | 1.29986 | negative regulation of transcription; nucleus; protein binding; regulation of growth; skeletal development; transcription corepressor activity |
| homeodomain interacting protein kinase 2 | 15258 | 1.80352 | ATP binding; PML body; cytoplasm; kinase activity; negative regulation of transcription from Pol II promoter; nucleus; protein amino acid phosphorylation; protein kinase activity; protein serine/threonine kinase activity; transcription corepressor activity; transferase activity |
| syndecan 2 | 15529 | 2.45969 | cytoskeletal protein binding; integral to membrane; membrane |
| insulin-like growth factor binding protein 6 | 16012 | 1.5537 | extracellular; extracellular space; growth factor binding; insulin-like growth factor binding; regulation of cell growth |
| low density lipoprotein receptor | 16835 | 1.85977 | calcium ion binding; cholesterol homeostasis; cholesterol metabolism; coated pit; endocytosis; endosome; extracellular space; integral to membrane; lipid transport; lipid transporter activity; low-density lipoprotein receptor activity; membrane; protein binding; receptor activity |
| LIM domain only 4 | 16911 | 2.67317 | protein binding; transcription factor binding; transcription factor complex; transcription from Pol II promoter |
| solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2 | 17254 | 1.61002 | alpha-amylase activity; carbohydrate metabolism; integral to membrane; protein binding |
| membrane protein, palmitoylated | 17524 | 4.21544 | membrane; protein binding |
| Max interacting protein 1 | 17859 | 3.72034 | DNA binding; nucleus; protein binding; regulation of transcription, DNA-dependent |
| myosin IC | 17913 | 1.61509 | ATP binding; actin binding; calmodulin binding; cytoskeleton organization and biogenesis; motor activity; myosin; myosin I; transport |
| sequestosome 1 | 18412 | 1.72511 | transcription cofactor activity |
| pallidin | 18457 | 3.60363 | endosome; membrane; membrane fusion; protein binding; vesicle docking during the process of exocytosis; vesicle fusion |
| platelet-activating factor acetylhydrolase, isoform 1b, beta1 subunit | 18472 | 1.58729 | 1-alkyl-2-acetylglycerophosphocholine esterase activity; acrosome formation; cell migration; centrosome; cytoplasm; hydrolase activity; microtubule associated complex; microtubule binding; microtubule cytoskeleton; neuroblast proliferation; neurogenesis; retrograde axon cargo transport |
| CCR4-NOT transcription complex, subunit 7 | 18983 | 2.45237 | CCR4-NOT complex; nucleus; positive regulation of transcription from Pol II promoter; protein binding; regulation of transcription, DNA-dependent; transcriptional activator activity |
| protective protein for beta-galactosidase | 19025 | 1.40582 | carboxypeptidase C activity; carboxypeptidase activity; catalytic activity; hydrolase activity; lysosome; protein binding; proteolysis and peptidolysis; serine carboxypeptidase activity |
| protein tyrosine phosphatase, non-receptor type substrate 1 | 19261 | 2.09061 | actin filament organization; cell motility; cell-matrix adhesion; cytoskeleton organization and biogenesis; extracellular space; integral to membrane; integral to plasma membrane; phagocytosis, binding; phagocytosis, engulfment; phosphoprotein amino acid binding; positive regulation of phagocytosis; protein binding |
| RAB10, member RAS oncogene family | 19325 | 2.65846 | Golgi apparatus; intracellular; intracellular protein transport; protein binding |
| retinoblastoma-like 1 (p107) | 19650 | 1.79321 | cell cycle; negative regulation of cell cycle; nucleus; protein binding; regulation of transcription, DNA-dependent; transcription factor complex |
| v-rel reticuloendotheliosis viral oncogene homolog A (avian) | 19697 | 1.63241 | DNA binding; cell growth and/or maintenance; cytoplasm; defense response; nucleus; organogenesis; positive regulation of interleukin-12 biosynthesis; positive regulation of transcription, DNA-dependent; protein binding; regulation of cell cycle; regulation of transcription, DNA-dependent; transcription factor activity; transcriptional activator activity |
| ring finger protein 1 | 19763 | 1.8625 | chromatin modification; nuclear body; nucleus; protein binding; regulation of transcription, DNA-dependent; transcriptional repressor activity; zinc ion binding |
| SH3-domain GRB2-like 1 | 20405 | 1.51428 | protein binding |
| SH3 domain protein 4 | 20410 | 2.20579 | cell adhesion; cytoskeleton; protein binding |
| SNAP-associated protein | 20615 | 2.23676 | SNARE binding; exocytosis; synapse; synaptic vesicle exocytosis; synaptosome |
| syntrophin, basic 2 | 20650 | 1.87455 | actin binding; calcium ion binding; calmodulin binding; cytoskeleton; membrane; protein binding; synapse |
| basic helix-loop-helix domain containing, class B2 | 20893 | 1.70733 | DNA binding; negative regulation of transcription, DNA-dependent; nucleus; protein binding; regulation of transcription, DNA-dependent; transcriptional repressor activity |
| TATA box binding protein | 21374 | 2.01117 | DNA binding; RNA polymerase I transcription factor complex; RNA polymerase II transcription factor activity; nucleus; protein binding; regulation of transcription, DNA-dependent; transcription; transcription factor TFIID complex; transcription factor activity; transcription factor complex; transcription initiation from Pol II promoter |
| upstream binding transcription factor, RNA polymerase I | 21429 | 1.7925 | DNA binding; nucleolus; nucleus; protein binding; regulation of transcription, DNA-dependent; transcription factor activity; transcription factor complex |
| thyrotroph embryonic factor | 21685 | 2.10475 | double-stranded DNA binding; nucleus; positive regulation of transcription from Pol II promoter; protein binding; transcriptional activator activity |
| tight junction protein 1 | 21872 | 2.33747 | adherens junction; intercellular canaliculus; membrane; plasma membrane; protein binding; tight junction |
| transformation related protein 53 | 22059 | 1.52863 | DNA binding; DNA damage response, signal transduction by p53 class mediator; apoptosis; cytoplasm; cytosol; negative regulation of cell cycle; nucleus; protein binding; protein-nucleus import, translocation; regulation of cell proliferation; regulation of transcription, DNA-dependent; transcription; transcription factor activity |
| unc-5 homolog C (C. elegans) | 22253 | 1.38149 | brain development; extracellular space; integral to membrane; netrin receptor activity; plasma membrane; protein binding; regulation of cell migration; signal transduction |
| zinc finger protein, multitype 2 | 22762 | 2.28297 | cytoplasm; negative regulation of transcription from Pol II promoter; nucleic acid binding; nucleus; transcription corepressor activity |
| coronin, actin binding protein 1B | 23789 | 3.15773 | actin binding |
| coronin, actin binding protein 1C | 23790 | 1.78542 | actin binding; actin cortical patch assembly; actin modulating activity; cytoskeleton; phagocytosis |
| protein kinase C and casein kinase substrate in neurons 2 | 23970 | 1.51247 | NOT Golgi trans face; cytoplasm; cytoskeletal protein binding; cytosol; endocytosis; negative regulation of endocytosis; protein binding; signal transduction |
| mitogen activated protein kinase 3 | 26417 | 1.36076 | ATP binding; MAP kinase activity; cell cycle; cytoplasm; kinase activity; nucleus; organogenesis; phosphorylation; phosphotyrosine binding; protein amino acid phosphorylation; protein binding; protein kinase activity; protein serine/threonine kinase activity; protein-tyrosine kinase activity; signal transduction; transferase activity |
| G protein-coupled receptor kinase-interactor 2 | 26431 | 1.80547 | DNA binding; GTPase activator activity; kinase activity; nucleus; protein binding; receptor activity |
| IQ motif containing GTPase activating protein 1 | 29875 | 1.74964 | Ras GTPase activator activity; calmodulin binding; cytoplasm; small GTPase mediated signal transduction |
| RING1 and YY1 binding protein | 56353 | 2.08641 | negative regulation of transcription from Pol II promoter; nucleoplasm; nucleus; protein binding; transcription corepressor activity |
| DnaJ (Hsp40) homolog, subfamily C, member 7 | 56354 | 1.49854 | chaperone activity; protein binding; protein folding |
| REC8-like 1 (yeast) | 56739 | 1.73159 | meiosis; nucleus; protein binding; synaptonemal complex |
| RIKEN cDNA E130014G12 gene | 56805 | 3.4174 | nucleus; protein binding; transcription |
| melanoma antigen, family D, 1 | 94275 | 2.94894 | cellular_component unknown; protein binding; regulation of transcription from Pol II promoter; transcription coactivator activity |